ANGI-14. A GSK-3/b-CATENIN/ARHGAP AXIS REGULATES GLIOBLASTOMA INVASION

INTRODUCTION: Glycogen synthase kinase-3 (GSK-3) has been implicated as a potential target in glioblastoma migration and invasion. Here we investigated the effects of GSK-3 inhibition on downstream effector genes and discovered a novel GSK-3 /b-catenin/ARHGAP migration axis that drives glioblastoma...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Brüning-Richardson, Anke, Mittelbronn, Michel, Humphries, Matthew, Esteves, Filomena, Boissinot, Marjorie, Tams, Daniel, Droop, Alastair, Cockle, Julia, Taylor, Sophie, Morton, Ruth, Ismail, Azzam, Lawler, Sean E, Mavria, Georgia, Short, Susan C
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692520/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.092
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