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Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma

Angiogenesis inhibitors targeting the VEGF signaling pathway have been US FDA approved for various cancers including glioblastoma (GBM), one of the most lethal and angiogenic tumors. This has led to the routine use of the anti-VEGF antibody bevacizumab in recurrent GBM, conveying substantial improve...

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Autori principali: Lu, Kan V, Bergers, Gabriele
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Medicine Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673744/
https://ncbi.nlm.nih.gov/pubmed/23750318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns.12.36
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