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Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma

Angiogenesis inhibitors targeting the VEGF signaling pathway have been US FDA approved for various cancers including glioblastoma (GBM), one of the most lethal and angiogenic tumors. This has led to the routine use of the anti-VEGF antibody bevacizumab in recurrent GBM, conveying substantial improve...

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Detalhes bibliográficos
Main Authors: Lu, Kan V, Bergers, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673744/
https://ncbi.nlm.nih.gov/pubmed/23750318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns.12.36
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