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Mechanisms of Neovascularization and Resistance to Anti-angiogenic Therapies in Glioblastoma Multiforme

Glioblastoma Multiforme (GBM) is the most malignant brain tumor and highly resistant to intensive combination therapies. GBM is one of the most vascularized tumors and vascular endothelial growth factor (VEGF) produced by tumor cells is a major factor regulating angiogenesis. Successful results of p...

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Bibliographic Details
Main Authors: Soda, Yasushi, Myskiw, Chad, Rommel, Amy, Verma, Inder M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665343/
https://ncbi.nlm.nih.gov/pubmed/23512266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-1019-z
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