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Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma

Angiogenesis inhibitors targeting the VEGF signaling pathway have been US FDA approved for various cancers including glioblastoma (GBM), one of the most lethal and angiogenic tumors. This has led to the routine use of the anti-VEGF antibody bevacizumab in recurrent GBM, conveying substantial improve...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lu, Kan V, Bergers, Gabriele
Format: Artigo
Sprache:Inglês
Veröffentlicht: Future Medicine Ltd 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673744/
https://ncbi.nlm.nih.gov/pubmed/23750318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns.12.36
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