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Modes of resistance to anti-angiogenic therapy

Angiogenesis inhibitors targeting the vascular endothelial growth factor (VEGF) signalling pathways are affording demonstrable therapeutic efficacy in mouse models of cancer and in an increasing number of human cancers. However, in both preclinical and clinical settings, the benefits are at best tra...

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Detalhes bibliográficos
Main Authors: Bergers, Gabriele, Hanahan, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874834/
https://ncbi.nlm.nih.gov/pubmed/18650835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2442
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