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Glioblastoma multiforme: an emerging paradigm of anti-VEGF therapy

BACKGROUND: Adults with malignant glioma, especially the most common subtype, glioblastoma multiforme, have an unacceptably poor outcome with current therapies. Malignant gliomas are amongst the most angiogenic of cancers, and VEGF is the dominant angiogenic mediator in these tumors. OBJECTIVE: To s...

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Bibliografiske detaljer
Main Authors: Reardon, David A, Wen, Patrick Y, Desjardins, Annick, Batchelor, Tracy T, Vredenburgh, James J
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871667/
https://ncbi.nlm.nih.gov/pubmed/18352856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.8.4.541
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