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Glioblastoma multiforme: an emerging paradigm of anti-VEGF therapy

BACKGROUND: Adults with malignant glioma, especially the most common subtype, glioblastoma multiforme, have an unacceptably poor outcome with current therapies. Malignant gliomas are amongst the most angiogenic of cancers, and VEGF is the dominant angiogenic mediator in these tumors. OBJECTIVE: To s...

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Main Authors: Reardon, David A, Wen, Patrick Y, Desjardins, Annick, Batchelor, Tracy T, Vredenburgh, James J
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871667/
https://ncbi.nlm.nih.gov/pubmed/18352856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.8.4.541
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