The Association of Alternate VEGF Ligands with Resistance to Anti-VEGF Therapy in Metastatic Colorectal Cancer

BACKGROUND: Circulating angiogenic factors are altered in patients with mCRC receiving bevacizumab. Evaluation of alterations in levels of VEGF ligands may provide insights into possible resistance mechanisms. METHODS: PlGF, VEGF-A, VEGF-C, and VEGF-D were measured from two cohorts of patients. Sequ...

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Main Authors: Lieu, Christopher H., Tran, Hai, Jiang, Zhi-Qin, Mao, Muling, Overman, Michael J., Lin, E., Eng, Cathy, Morris, Jeffrey, Ellis, Lee, Heymach, John V., Kopetz, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797099/
https://ncbi.nlm.nih.gov/pubmed/24143206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077117
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