Impact of BRAF Mutation and Microsatellite Instability on the Pattern of Metastatic Spread and Prognosis in Metastatic Colorectal Cancer

BACKGROUND: It is hypothesized that BRAF mutant cancers represent a discrete subset of metastatic colorectal cancer (CRC) defined by poorer survival. This study investigates whether BRAF mutant CRC is further defined by a distinct pattern of metastatic spread and explores the impact of BRAF mutation...

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Gepubliceerd in:Cancer
Hoofdauteurs: Tran, Ben, Kopetz, Scott, Tie, Jeanne, Gibbs, Peter, Jiang, Zhi-Qin, Lieu, Christopher H, Agarwal, Atin, Maru, Dipen M, Sieber, Oliver, Desai, Jayesh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257471/
https://ncbi.nlm.nih.gov/pubmed/21456008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26086
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