Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1

Alkylating agents comprise a major class of front-line cancer chemotherapeutic compounds, and while these agents effectively kill tumor cells, they also damage healthy tissues. Although base excision repair (BER) is essential in repairing DNA alkylation damage, under certain conditions, initiation o...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Calvo, Jennifer A., Moroski-Erkul, Catherine A., Lake, Annabelle, Eichinger, Lindsey W., Shah, Dharini, Jhun, Iny, Limsirichai, Prajit, Bronson, Roderick T., Christiani, David C., Meira, Lisiane B., Samson, Leona D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617098/
https://ncbi.nlm.nih.gov/pubmed/23593019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003413
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