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Alkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombination
Somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin (Ig) genes require the cytosine deaminase AID, which deaminates cytosine to uracil in Ig gene DNA. Paradoxically, proteins involved normally in error-free base excision repair and mismatch repair, seem to be co-opted...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196218/ https://ncbi.nlm.nih.gov/pubmed/17681497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.06.012 |
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