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Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination
The primary antibody repertoire is generated by mechanisms involving the assembly of the exons that encode the antigen-binding variable regions of immunoglobulin heavy (IgH) and light (IgL) chains during the early development of B lymphocytes. After antigen-dependent activation, mature B lymphocytes...
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| Publicado en: | Microbiol Spectr |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4481323/ https://ncbi.nlm.nih.gov/pubmed/26104555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/microbiolspec.MDNA3-0037-2014 |
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