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V(D)J recombination, somatic hypermutation and class switch recombination of immunoglobulins: mechanism and regulation

Immunoglobulins emerging from B lymphocytes and capable of recognizing almost all kinds of antigens owing to the extreme diversity of their antigen‐binding portions, known as variable (V) regions, play an important role in immune responses. The exons encoding the V regions are known as V (variable),...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Chi, Xiying, Li, Yue, Qiu, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341547/
https://ncbi.nlm.nih.gov/pubmed/32031242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13176
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