Rapamycin extends life span of Rb1(+/−) mice by inhibiting neuroendocrine tumors

Chronic treatment of mice with an enterically released formulation of rapamycin (eRapa) extends median and maximum life span, partly by attenuating cancer. The mechanistic basis of this response is not known. To gain a better understanding of these in vivo effects, we used a defined preclinical mode...

詳細記述

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書誌詳細
主要な著者: Livi, Carolina B., Hardman, Rulon L., Christy, Barbara A., Dodds, Sherry G., Jones, Diane, Williams, Charnae, Strong, Randy, Bokov, Alex, Javors, Martin A., Ikeno, Yuji, Hubbard, Gene, Hasty, Paul, Sharp, Zelton Dave
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2013
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616197/
https://ncbi.nlm.nih.gov/pubmed/23454836
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