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Huntingtin’s Function in Axonal Transport Is Conserved in Drosophila melanogaster

Huntington’s disease (HD) is a devastating dominantly inherited neurodegenerative disorder caused by an abnormal polyglutamine expansion in the N-terminal part of the huntingtin (HTT) protein. HTT is a large scaffold protein that interacts with more than a hundred proteins and is probably involved i...

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Detalhes bibliográficos
Main Authors: Zala, Diana, Hinckelmann, Maria-Victoria, Saudou, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610688/
https://ncbi.nlm.nih.gov/pubmed/23555909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060162
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