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Huntingtin’s Function in Axonal Transport Is Conserved in Drosophila melanogaster
Huntington’s disease (HD) is a devastating dominantly inherited neurodegenerative disorder caused by an abnormal polyglutamine expansion in the N-terminal part of the huntingtin (HTT) protein. HTT is a large scaffold protein that interacts with more than a hundred proteins and is probably involved i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610688/ https://ncbi.nlm.nih.gov/pubmed/23555909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060162 |
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