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Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

The transport of vesicles in neurons is a highly regulated process, with vesicles moving either anterogradely or retrogradely depending on the nature of the molecular motors, kinesins and dynein, respectively, which propel vesicles along microtubules (MTs). However, the mechanisms that determine the...

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Detalhes bibliográficos
Main Authors: Colin, Emilie, Zala, Diana, Liot, Géraldine, Rangone, Hélène, Borrell-Pagès, Maria, Li, Xiao-Jiang, Saudou, Frédéric, Humbert, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516882/
https://ncbi.nlm.nih.gov/pubmed/18615096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.133
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