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Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

The transport of vesicles in neurons is a highly regulated process, with vesicles moving either anterogradely or retrogradely depending on the nature of the molecular motors, kinesins and dynein, respectively, which propel vesicles along microtubules (MTs). However, the mechanisms that determine the...

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Autori principali: Colin, Emilie, Zala, Diana, Liot, Géraldine, Rangone, Hélène, Borrell-Pagès, Maria, Li, Xiao-Jiang, Saudou, Frédéric, Humbert, Sandrine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516882/
https://ncbi.nlm.nih.gov/pubmed/18615096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.133
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