Huntingtin Acts Non Cell-Autonomously on Hippocampal Neurogenesis and Controls Anxiety-Related Behaviors in Adult Mouse

Huntington’s disease (HD) is a fatal neurodegenerative disease, characterized by motor defects and psychiatric symptoms, including mood disorders such as anxiety and depression. HD is caused by an abnormal polyglutamine (polyQ) expansion in the huntingtin (HTT) protein. The development and analysis...

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Bibliografske podrobnosti
Main Authors: Pla, Patrick, Orvoen, Sophie, Benstaali, Caroline, Dodier, Sophie, Gardier, Alain M., David, Denis J., Humbert, Sandrine, Saudou, Frédéric
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760801/
https://ncbi.nlm.nih.gov/pubmed/24019939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073902
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