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Mutant Huntingtin Alters Retrograde Transport of TrkB Receptors in Striatal Dendrites

Huntingtin (HTT), the protein mutated in Huntington's disease (HD), controls transport of the neurotrophin, brain-derived neurotrophic factor (BDNF), within corticostriatal neurons. Transport and delivery of BDNF to the striatum are reduced in disease, which contributes to striatal neuron degen...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Liot, Géraldine, Zala, Diana, Pla, Patrick, Mottet, Guillaume, Piel, Matthieu, Saudou, Frédéric
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619069/
https://ncbi.nlm.nih.gov/pubmed/23575829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2033-12.2013
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