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Mutant huntingtin enhances activation of dendritic Kv4 K(+) channels in striatal spiny projection neurons
Huntington’s disease (HD) is initially characterized by an inability to suppress unwanted movements, a deficit attributable to impaired synaptic activation of striatal indirect pathway spiny projection neurons (iSPNs). To better understand the mechanisms underlying this deficit, striatal neurons in...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6481990/ https://ncbi.nlm.nih.gov/pubmed/31017573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40818 |
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