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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

The neurobiological functions of a number of kinases expressed in the brain are unknown. Here, we report new findings on DCLK3 (doublecortin like kinase 3), which is preferentially expressed in neurons in the striatum and dentate gyrus. Its function has never been investigated. DCLK3 expression is m...

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Bibliografske podrobnosti
izdano v:Brain
Main Authors: Galvan, Laurie, Francelle, Laetitia, Gaillard, Marie-Claude, de Longprez, Lucie, Carrillo-de Sauvage, Maria-Angeles, Liot, Géraldine, Cambon, Karine, Stimmer, Lev, Luccantoni, Sophie, Flament, Julien, Valette, Julien, de Chaldée, Michel, Auregan, Gwenaelle, Guillermier, Martine, Joséphine, Charlène, Petit, Fanny, Jan, Caroline, Jarrige, Margot, Dufour, Noëlle, Bonvento, Gilles, Humbert, Sandrine, Saudou, Frédéric, Hantraye, Philippe, Merienne, Karine, Bemelmans, Alexis-Pierre, Perrier, Anselme L, Déglon, Nicole, Brouillet, Emmanuel
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917821/
https://ncbi.nlm.nih.gov/pubmed/29534157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy057
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