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Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) facilitates fast axonal transport in neurons. However, given that GAPDH does not produce ATP, it is unclear whether glycolysis per se is sufficient to propel vesicles. Although many proteins regulating transport have been identif...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hinckelmann, María-Victoria, Virlogeux, Amandine, Niehage, Christian, Poujol, Christel, Choquet, Daniel, Hoflack, Bernard, Zala, Diana, Saudou, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078996/
https://ncbi.nlm.nih.gov/pubmed/27775035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13233
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