Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) facilitates fast axonal transport in neurons. However, given that GAPDH does not produce ATP, it is unclear whether glycolysis per se is sufficient to propel vesicles. Although many proteins regulating transport have been identif...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Hinckelmann, María-Victoria, Virlogeux, Amandine, Niehage, Christian, Poujol, Christel, Choquet, Daniel, Hoflack, Bernard, Zala, Diana, Saudou, Frédéric
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078996/
https://ncbi.nlm.nih.gov/pubmed/27775035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13233
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