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Characterization of axonal transport defects in Drosophila Huntingtin mutants

Polyglutamine (polyQ) expansion within Huntingtin (Htt) causes the fatal neurodegenerative disorder Huntington’s Disease (HD). Although Htt is ubiquitously expressed and conserved from Drosophila to humans, its normal biological function is still being elucidated. Here we characterize a role for the...

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Bibliografiska uppgifter
I publikationen:J Neurogenet
Huvudupphovsmän: Weiss, Kurt R., Littleton, J. Troy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525331/
https://ncbi.nlm.nih.gov/pubmed/27309588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01677063.2016.1202950
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