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Characterization of axonal transport defects in Drosophila Huntingtin mutants

Polyglutamine (polyQ) expansion within Huntingtin (Htt) causes the fatal neurodegenerative disorder Huntington’s Disease (HD). Although Htt is ubiquitously expressed and conserved from Drosophila to humans, its normal biological function is still being elucidated. Here we characterize a role for the...

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Detalhes bibliográficos
Publicado no:J Neurogenet
Main Authors: Weiss, Kurt R., Littleton, J. Troy
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525331/
https://ncbi.nlm.nih.gov/pubmed/27309588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01677063.2016.1202950
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