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Axonal transport defects are a common phenotype in Drosophila models of ALS

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons resulting in a catastrophic loss of motor function. Current therapies are severely limited owing to a poor mechanistic understanding of the pathobiology. Mutations in a large number of genes have now been linke...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Baldwin, Katie R., Godena, Vinay K., Hewitt, Victoria L., Whitworth, Alexander J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181624/
https://ncbi.nlm.nih.gov/pubmed/27056981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw105
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