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Modeling Huntington disease in Drosophila: Insights into axonal transport defects and modifiers of toxicity
Huntington disease (HD) is an inherited neurodegenerative disorder caused by a polyglutamine (polyQ) expansion in the huntingtin (Htt) gene. Despite years of research, there is no treatment that extends life for patients with the disorder. Similarly, little is known about which cellular pathways tha...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Landes Bioscience
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896494/ https://ncbi.nlm.nih.gov/pubmed/24022020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/fly.26279 |
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