Enhanced Sensitivity of Striatal Neurons to Axonal Transport Defects Induced by Mutant Huntingtin

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease linked to a polyQ (polyglutamine) expansion in the huntingtin protein. Although general brain atrophy is found in HD patients, the striatum is the most severely affected region. Loss or mutant forms of huntingtin were...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Her, Lu-Shiun, Goldstein, Lawrence S. B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2008
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671757/
https://ncbi.nlm.nih.gov/pubmed/19074039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4144-08.2008
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