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Characterization of axonal transport defects in Drosophila Huntingtin mutants

Polyglutamine (polyQ) expansion within Huntingtin (Htt) causes the fatal neurodegenerative disorder Huntington’s Disease (HD). Although Htt is ubiquitously expressed and conserved from Drosophila to humans, its normal biological function is still being elucidated. Here we characterize a role for the...

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Detaylı Bibliyografya
Yayımlandı:J Neurogenet
Asıl Yazarlar: Weiss, Kurt R., Littleton, J. Troy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525331/
https://ncbi.nlm.nih.gov/pubmed/27309588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01677063.2016.1202950
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