Huntingtin-mediated axonal transport requires arginine methylation by PRMT6

The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development throughout life. To better understand how HTT mediates axonal transport and why this function is disrupted in Huntington’s disease (HD), we study vesicle-associa...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Migazzi, Alice, Scaramuzzino, Chiara, Anderson, Eric N., Tripathy, Debasmita, Hernández, Ivó H., Grant, Rogan A., Roccuzzo, Michela, Tosatto, Laura, Virlogeux, Amandine, Zuccato, Chiara, Caricasole, Andrea, Ratovitski, Tamara, Ross, Christopher A., Pandey, Udai B., Lucas, José J., Saudou, Frédéric, Pennuto, Maria, Basso, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132453/
https://ncbi.nlm.nih.gov/pubmed/33852844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108980
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