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A multifunctional, multi-pathway intracellular localization signal in Huntingtin
Nuclear accumulation of the polyglutamine-expanded mutant huntingtin protein remains one of the most predictive cell biological phenotypes of Huntington’s disease (HD) progression in patient brain samples and mouse models of the disease. Yet, the relationship between huntingtin nuclear import, neuro...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609847/ https://ncbi.nlm.nih.gov/pubmed/23750301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.23318 |
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