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A multifunctional, multi-pathway intracellular localization signal in Huntingtin
Nuclear accumulation of the polyglutamine-expanded mutant huntingtin protein remains one of the most predictive cell biological phenotypes of Huntington’s disease (HD) progression in patient brain samples and mouse models of the disease. Yet, the relationship between huntingtin nuclear import, neuro...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609847/ https://ncbi.nlm.nih.gov/pubmed/23750301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.23318 |
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