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A multifunctional, multi-pathway intracellular localization signal in Huntingtin

Nuclear accumulation of the polyglutamine-expanded mutant huntingtin protein remains one of the most predictive cell biological phenotypes of Huntington’s disease (HD) progression in patient brain samples and mouse models of the disease. Yet, the relationship between huntingtin nuclear import, neuro...

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Bibliografiska uppgifter
Huvudupphovsmän: Desmond, Carly R., Maiuri, Tamara, Truant, Ray
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609847/
https://ncbi.nlm.nih.gov/pubmed/23750301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.23318
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