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A multifunctional, multi-pathway intracellular localization signal in Huntingtin

Nuclear accumulation of the polyglutamine-expanded mutant huntingtin protein remains one of the most predictive cell biological phenotypes of Huntington’s disease (HD) progression in patient brain samples and mouse models of the disease. Yet, the relationship between huntingtin nuclear import, neuro...

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Detalhes bibliográficos
Main Authors: Desmond, Carly R., Maiuri, Tamara, Truant, Ray
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609847/
https://ncbi.nlm.nih.gov/pubmed/23750301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.23318
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