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Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering
Protease-activated receptor-2 (PAR(2)) is a G-protein coupled receptor (GPCR) associated with a variety of pathologies. However, the therapeutic potential of PAR(2) is limited by a lack of potent and specific ligands. Following proteolytic cleavage, PAR(2) is activated through a tethered ligand. Hen...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , |
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| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Federation of American Societies for Experimental Biology
2013
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606532/ https://ncbi.nlm.nih.gov/pubmed/23292071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217323 |
| ট্যাগগুলো: |
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