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A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca(2+)-regulated ion conductance

The airway epithelium provides a barrier that separates inhaled air and its various particulates from the underlying tissues. It provides key physiological functions in both sensing the environment and initiating appropriate innate immune defenses to protect the lung. Protease-activated receptor-2 (...

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Hlavní autoři: Sherwood, Cara L., Daines, Michael O., Price, Theodore J., Vagner, Josef, Boitano, Scott
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199996/
https://ncbi.nlm.nih.gov/pubmed/25143347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00257.2014
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