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A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca(2+)-regulated ion conductance

The airway epithelium provides a barrier that separates inhaled air and its various particulates from the underlying tissues. It provides key physiological functions in both sensing the environment and initiating appropriate innate immune defenses to protect the lung. Protease-activated receptor-2 (...

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Autores principales: Sherwood, Cara L., Daines, Michael O., Price, Theodore J., Vagner, Josef, Boitano, Scott
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199996/
https://ncbi.nlm.nih.gov/pubmed/25143347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00257.2014
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