Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase

Lymphocyte depletion with antithymocyte globulin (ATG) can be complicated by systemic coagulation activation. We found that ATG activated tissue factor procoagulant activity (TF PCA) on monocytic cells more potently than other stimuli that decrypt TF, including cell disruption, TF pathway inhibitor...

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Bibliographic Details
Main Authors: Langer, Florian, Spath, Brigitte, Fischer, Cornelia, Stolz, Moritz, Ayuk, Francis A., Kröger, Nicolaus, Bokemeyer, Carsten, Ruf, Wolfram
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2013
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606067/
https://ncbi.nlm.nih.gov/pubmed/23315166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460493
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