Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase

Lymphocyte depletion with antithymocyte globulin (ATG) can be complicated by systemic coagulation activation. We found that ATG activated tissue factor procoagulant activity (TF PCA) on monocytic cells more potently than other stimuli that decrypt TF, including cell disruption, TF pathway inhibitor...

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Autori principali: Langer, Florian, Spath, Brigitte, Fischer, Cornelia, Stolz, Moritz, Ayuk, Francis A., Kröger, Nicolaus, Bokemeyer, Carsten, Ruf, Wolfram
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606067/
https://ncbi.nlm.nih.gov/pubmed/23315166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460493
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