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Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure

Tissue factor (TF) is the cellular receptor for plasma protease factor VIIa (FVIIa), and the TF-FVIIa complex initiates coagulation in both hemostasis and thrombosis. Cell surface-exposed TF is mainly cryptic and requires activation to fully exhibit the procoagulant potential. Recently, the protein...

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Detalhes bibliográficos
Main Authors: Popescu, Narcis I., Lupu, Cristina, Lupu, Florea
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924232/
https://ncbi.nlm.nih.gov/pubmed/20448108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-249607
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