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Temporal and spatial characterization of nonsense-mediated mRNA decay
Nonsense-mediated mRNA decay (NMD) is a quality control mechanism responsible for “surveying” mRNAs during translation and degrading those that harbor a premature termination codon (PTC). Currently the intracellular spatial location of NMD and the kinetics of its decay step in mammalian cells are un...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605467/ https://ncbi.nlm.nih.gov/pubmed/23431032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.209635.112 |
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