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Nonsense-mediated mRNA Decay and Cancer
Nonsense-mediated mRNA decay (NMD) is a conserved mRNA surveillance pathway that cells use to ensure the quality of transcripts and to fine-tune transcript abundance. The role of NMD in cancer development is complex. In some cases, tumors have exploited NMD to downregulate gene expression by apparen...
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| Опубликовано в: : | Curr Opin Genet Dev |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869107/ https://ncbi.nlm.nih.gov/pubmed/29121514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.10.007 |
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