Chargement en cours...

Nonsense-mediated mRNA Decay and Cancer

Nonsense-mediated mRNA decay (NMD) is a conserved mRNA surveillance pathway that cells use to ensure the quality of transcripts and to fine-tune transcript abundance. The role of NMD in cancer development is complex. In some cases, tumors have exploited NMD to downregulate gene expression by apparen...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Curr Opin Genet Dev
Auteurs principaux: Popp, Maximilian W., Maquat, Lynne E.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869107/
https://ncbi.nlm.nih.gov/pubmed/29121514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.10.007
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!