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Organizing Principles of Mammalian Nonsense-Mediated mRNA Decay
Cells use messenger RNAs (mRNAs) to ensure the accurate dissemination of genetic information encoded by DNA. Given that mRNAs largely direct the synthesis of a critical effector of cellular phenotype, i.e., proteins, tight regulation of both the quality and quantity of mRNA is a prerequisite for eff...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148824/ https://ncbi.nlm.nih.gov/pubmed/24274751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-111212-133424 |
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