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The Dharma of Nonsense-Mediated mRNA Decay in Mammalian Cells

Mammalian-cell messenger RNAs (mRNAs) are generated in the nucleus from precursor RNAs (pre-mRNAs, which often contain one or more introns) that are complexed with an array of incompletely inventoried proteins. During their biogenesis, pre-mRNAs and their derivative mRNAs are subject to extensive ci...

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Detalhes bibliográficos
Main Authors: Popp, Maximilian Wei-Lin, Maquat, Lynne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Korea Society for Molecular and Cellular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907001/
https://ncbi.nlm.nih.gov/pubmed/24552703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.2193
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