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Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine
Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA quality control and regulatory process that plays direct roles in human health and disease. In this Minireview, we discuss how understanding the molecular events that trigger NMD can facilitate strategic targeting of genes via CRISPR/Cas9 techn...
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| 出版年: | Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4924582/ https://ncbi.nlm.nih.gov/pubmed/27259145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.053 |
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