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Nonsense-mediated mRNA decay in humans at a glance

Nonsense-mediated mRNA decay (NMD) is an mRNA quality-control mechanism that typifies all eukaryotes examined to date. NMD surveys newly synthesized mRNAs and degrades those that harbor a premature termination codon (PTC), thereby preventing the production of truncated proteins that could result in...

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書目詳細資料
發表在:J Cell Sci
Main Authors: Kurosaki, Tatsuaki, Maquat, Lynne E.
格式: Artigo
語言:Inglês
出版: The Company of Biologists Ltd 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760306/
https://ncbi.nlm.nih.gov/pubmed/26787741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181008
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