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Defining nonsense-mediated mRNA decay intermediates in human cells
Nonsense-mediated mRNA decay (NMD) is a cellular mRNA degradation mechanism that inhibits the expression of aberrant mRNAs harboring premature termination codons (PTCs). Recent progress in transcriptome-wide sequencing techniques has revealed that NMD also degrades approximately 5–30% of non-mutated...
Guardat en:
| Publicat a: | Methods |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6855378/ https://ncbi.nlm.nih.gov/pubmed/30576707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.12.005 |
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