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Temporal and spatial characterization of nonsense-mediated mRNA decay
Nonsense-mediated mRNA decay (NMD) is a quality control mechanism responsible for “surveying” mRNAs during translation and degrading those that harbor a premature termination codon (PTC). Currently the intracellular spatial location of NMD and the kinetics of its decay step in mammalian cells are un...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605467/ https://ncbi.nlm.nih.gov/pubmed/23431032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.209635.112 |
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