Llwytho...

Synthesis and biological activity of 5-chloro-N(4)-substituted phenyl-9H-pyrimido[4,5-b]indole-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic agents(1)

Inhibition of receptor tyrosine kinase (RTK) signaling pathways is an important area for the development of novel anticancer agents. Numerous multikinase inhibitors (MKIs) have been recently approved for the treatment of cancer. Vascular endothelial growth factor receptor-2 (VEGFR-2) is the principa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gangjee, Aleem, Zaware, Nilesh, Raghavan, Sudhir, Disch, Bryan C., Thorpe, Jessica E., Bastian, Anja, Ihnat, Michael A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602277/
https://ncbi.nlm.nih.gov/pubmed/23434139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.01.040
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