Design, synthesis and evaluation of 2-amino-4-m-bromoanilino-6-arylmethyl-7 H-pyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors and antiangiogenic agents1

由 Gangjee, Aleem, Zhao, Ying, Raghavan, Sudhir, Ihnat, Michael A., Disch, Bryan C.
出版 2010

Synthesis and biological activity of 5-chloro-N(4)-substituted phenyl-9H-pyrimido[4,5-b]indole-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangi...

由 Gangjee, Aleem, Zaware, Nilesh, Raghavan, Sudhir, Disch, Bryan C., Thorpe, Jessica E., Bastian, Anja, Ihnat, Michael A
出版 2013

Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor

由 Pathuri, Gopal, Thorpe, Jessica E., Disch, Bryan C., Bailey-Downs, Lora C., Ihnat, Michael A., Gali, Hariprasad
發表在 Bioorg Med Chem Lett (2013)

Discovery of Antitubulin Agents with Antiangiogenic Activity as Single Entities with Multitarget Chemotherapy Potential

由 Gangjee, Aleem, Pavana, Roheeth Kumar, Ihnat, Michael A., Thorpe, Jessica E., Disch, Bryan C., Bastian, Anja, Bailey-Downs, Lora C., Hamel, Ernest, Bai, Rouli
出版 2014

Development and Characterization of a Preclinical Model of Breast Cancer Lung Micrometastatic to Macrometastatic Progression

由 Bailey-Downs, Lora C., Thorpe, Jessica E., Disch, Bryan C., Bastian, Anja, Hauser, Paul J., Farasyn, Taleah, Berry, William L., Hurst, Robert E., Ihnat, Michael A.
出版 2014

A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer

由 Bastian, Anja, Thorpe, Jessica E., Disch, Bryan C., Bailey-Downs, Lora C., Gangjee, Aleem, Devambatla, Ravi K. V., Henthorn, Jim, Humphries, Kenneth M., Vadvalkar, Shraddha S., Ihnat, Michael A.
發表在 J Pharmacol Exp Ther (2015)

The Design and Discovery of Water Soluble 4-Substituted-2,6-dimethylfuro[2,3-d]pyrimidines as Multitargeted Receptor Tyrosine Kinase Inhibitors and Microtubule Targeting Antitumor...

由 Zhang, Xin, Raghavan, Sudhir, Ihnat, Michael, Thorpe, Jessica E., Disch, Bryan C., Bastian, Anja, Bailey-Downs, Lora C., Dybdal-Hargreaves, Nicholas F., Rohena, Cristina C., Hamel, Ernest, Mooberry, Susan L., Gangjee, Aleem
出版 2014