Novel tricyclic indeno[2, 1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents

بواسطة Gangjee, Aleem, Zhao, Ying, Ihnat, Michael A., Thorpe, Jessica E., Bailey-Downs, Lora C., Kisliuk, Roy L.
منشور في 2012

N(2)-Trimethylacetyl substituted and unsubstituted-N(4)-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: Design, cellular receptor tyrosine kinas...

بواسطة Gangjee, Aleem, Namjoshi, Ojas A., Yu, Jianming, Ihnat, Michael A., Thorpe, Jessica E., Bailey-Downs, Lora C.
منشور في 2013

Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor

بواسطة Pathuri, Gopal, Thorpe, Jessica E., Disch, Bryan C., Bailey-Downs, Lora C., Ihnat, Michael A., Gali, Hariprasad
الحاوية / القاعدة Bioorg Med Chem Lett (2013)

Aging Exacerbates Obesity-Induced Oxidative Stress and Inflammation in Perivascular Adipose Tissue in Mice: A Paracrine Mechanism Contributing to Vascular Redox Dysregulation and I...

بواسطة Bailey-Downs, Lora C., Tucsek, Zsuzsanna, Toth, Peter, Sosnowska, Danuta, Gautam, Tripti, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
منشور في 2013

Discovery of Antitubulin Agents with Antiangiogenic Activity as Single Entities with Multitarget Chemotherapy Potential

بواسطة Gangjee, Aleem, Pavana, Roheeth Kumar, Ihnat, Michael A., Thorpe, Jessica E., Disch, Bryan C., Bastian, Anja, Bailey-Downs, Lora C., Hamel, Ernest, Bai, Rouli
منشور في 2014

Development and Characterization of a Preclinical Model of Breast Cancer Lung Micrometastatic to Macrometastatic Progression

بواسطة Bailey-Downs, Lora C., Thorpe, Jessica E., Disch, Bryan C., Bastian, Anja, Hauser, Paul J., Farasyn, Taleah, Berry, William L., Hurst, Robert E., Ihnat, Michael A.
منشور في 2014

A Small Molecule with Anticancer and Antimetastatic Activities Induces Rapid Mitochondrial-Associated Necrosis in Breast Cancer

بواسطة Bastian, Anja, Thorpe, Jessica E., Disch, Bryan C., Bailey-Downs, Lora C., Gangjee, Aleem, Devambatla, Ravi K. V., Henthorn, Jim, Humphries, Kenneth M., Vadvalkar, Shraddha S., Ihnat, Michael A.
الحاوية / القاعدة J Pharmacol Exp Ther (2015)

Identification of novel drugs to target dormant micrometastases

بواسطة Hurst, Robert E., Hauser, Paul J., You, Youngjae, Bailey-Downs, Lora C., Bastian, Anja, Matthews, Stephen M., Thorpe, Jessica, Earle, Christine, Bourguignon, Lilly Y. W., Ihnat, Michael A.
الحاوية / القاعدة BMC Cancer (2015)

Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: A potential model of geriatric depression

بواسطة Mitschelen, Matthew, Yan, Han, Farley, Julie A., Warrington, Junie P., Han, Song, Hereñú, Claudia B., Csiszar, Anna, Ungvari, Zoltan, Bailey-Downs, Lora C., Bass, Caroline E., Sonntag, William E.
منشور في 2011

Growth Hormone and IGF-1 Deficiency Exacerbate High-Fat Diet–Induced Endothelial Impairment in Obese Lewis Dwarf Rats: Implications for Vascular Aging

بواسطة Bailey-Downs, Lora C., Sosnowska, Danuta, Toth, Peter, Mitschelen, Matthew, Gautam, Tripti, Henthorn, Jim C., Ballabh, Praveen, Koller, Akos, Farley, Julie A., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
منشور في 2012

17α‐estradiol acts through hypothalamic pro‐opiomelanocortin expressing neurons to reduce feeding behavior

بواسطة Steyn, Frederik J., Ngo, Shyuan T., Chen, Vicky Ping, Bailey‐Downs, Lora C., Xie, Teresa Y., Ghadami, Martin, Brimijoin, Stephen, Freeman, Willard M., Rubinstein, Marcelo, Low, Malcolm J., Stout, Michael B.
الحاوية / القاعدة Aging Cell (2017)

The Design and Discovery of Water Soluble 4-Substituted-2,6-dimethylfuro[2,3-d]pyrimidines as Multitargeted Receptor Tyrosine Kinase Inhibitors and Microtubule Targeting Antitumor...

بواسطة Zhang, Xin, Raghavan, Sudhir, Ihnat, Michael, Thorpe, Jessica E., Disch, Bryan C., Bastian, Anja, Bailey-Downs, Lora C., Dybdal-Hargreaves, Nicholas F., Rohena, Cristina C., Hamel, Ernest, Mooberry, Susan L., Gangjee, Aleem
منشور في 2014

Liver-Specific Knockdown of IGF-1 Decreases Vascular Oxidative Stress Resistance by Impairing the Nrf2-Dependent Antioxidant Response: A Novel Model of Vascular Aging

بواسطة Bailey-Downs, Lora C., Mitschelen, Matthew, Sosnowska, Danuta, Toth, Peter, Pinto, John T., Ballabh, Praveen, Valcarcel-Ares, M.Noa, Farley, Julie, Koller, Akos, Henthorn, Jim C., Bass, Caroline, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna
منشور في 2012