Discovery of Antitubulin Agents with Antiangiogenic Activity as Single Entities with Multitarget Chemotherapy Potential

[Image: see text] Antiangiogenic agents (AA) are cytostatic, and their utility in cancer chemotherapy lies in their combination with cytotoxic chemotherapeutic agents. Clinical combinations of vascular endothelial growth factor receptor-2 (VEGFR2) inhibitors with antitubulin agents have been particu...

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Main Authors: Gangjee, Aleem, Pavana, Roheeth Kumar, Ihnat, Michael A., Thorpe, Jessica E., Disch, Bryan C., Bastian, Anja, Bailey-Downs, Lora C., Hamel, Ernest, Bai, Rouli
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027584/
https://ncbi.nlm.nih.gov/pubmed/24900865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4004793
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