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The p90 Ribosomal S6 Kinase (RSK) Is a Mediator of Smooth Muscle Contractility

In the canonical model of smooth muscle (SM) contraction, the contractile force is generated by phosphorylation of the myosin regulatory light chain (RLC(20)) by the myosin light chain kinase (MLCK). Moreover, phosphorylation of the myosin targeting subunit (MYPT1) of the RLC(20) phosphatase (MLCP)...

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Autors principals: Artamonov, Mykhaylo, Momotani, Ko, Utepbergenov, Darkhan, Franke, Aaron, Khromov, Alexander, Derewenda, Zygmunt S., Somlyo, Avril V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596281/
https://ncbi.nlm.nih.gov/pubmed/23516539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058703
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